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A systematic comparison of recurrent event models for application to composite endpoints

BACKGROUND: Many clinical trials focus on the comparison of the treatment effect between two or more groups concerning a rarely occurring event. In this situation, showing a relevant effect with an acceptable power requires the observation of a large number of patients over a long period of time. Fo...

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Detalles Bibliográficos
Autores principales: Ozga, Ann-Kathrin, Kieser, Meinhard, Rauch, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755224/
https://www.ncbi.nlm.nih.gov/pubmed/29301487
http://dx.doi.org/10.1186/s12874-017-0462-x