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A systematic comparison of recurrent event models for application to composite endpoints
BACKGROUND: Many clinical trials focus on the comparison of the treatment effect between two or more groups concerning a rarely occurring event. In this situation, showing a relevant effect with an acceptable power requires the observation of a large number of patients over a long period of time. Fo...
Autores principales: | Ozga, Ann-Kathrin, Kieser, Meinhard, Rauch, Geraldine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755224/ https://www.ncbi.nlm.nih.gov/pubmed/29301487 http://dx.doi.org/10.1186/s12874-017-0462-x |
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