Hypercapnia induces IL-1β overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats

BACKGROUND: Cognitive impairment is one of common complications of acute respiratory distress syndrome (ARDS). Increasing evidence suggests that interleukin-1 beta (IL-1β) plays a role in inducing neuronal apoptosis in cognitive dysfunction. The lung protective ventilatory strategies, which serve to...

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Detalles Bibliográficos
Autores principales: Ding, Hong-Guang, Deng, Yi-Yu, Yang, Ren-qiang, Wang, Qiao-Sheng, Jiang, Wen-Qiang, Han, Yong-Li, Huang, Lin-Qiang, Wen, Miao-Yun, Zhong, Wen-Hong, Li, Xu-Sheng, Yang, Fan, Zeng, Hong-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755461/
https://www.ncbi.nlm.nih.gov/pubmed/29304864
http://dx.doi.org/10.1186/s12974-017-1051-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755461/
https://www.ncbi.nlm.nih.gov/pubmed/29304864
http://dx.doi.org/10.1186/s12974-017-1051-y

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