Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation

Mutations in the gene encoding emerin cause Emery-Dreifuss muscular dystrophy (EDMD), a disorder causing progressive skeletal muscle wasting, irregular heart rhythms and contractures of major tendons. RNA sequencing was performed on differentiating wildtype and emerin-null myogenic progenitors to id...

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Detalles Bibliográficos
Autores principales: Iyer, Ashvin, Koch, Adam J., Holaska, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755497/
https://www.ncbi.nlm.nih.gov/pubmed/29065506
http://dx.doi.org/10.3390/cells6040038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755497/
https://www.ncbi.nlm.nih.gov/pubmed/29065506
http://dx.doi.org/10.3390/cells6040038

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