Dissecting the telomere-inner nuclear membrane interface formed in meiosis

Tethering telomeres to the inner nuclear membrane (INM) allows for homologous chromosome pairing during meiosis. A meiosis-specific protein TERB1 binds the telomeric protein TRF1 to establish telomere-INM connectivity and is essential for mouse fertility. Here we solve the structure of the human TRF...

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Detalles Bibliográficos
Autores principales: Pendlebury, Devon F., Fujiwara, Yasuhiro, Tesmer, Valerie M., Smith, Eric M., Shibuya, Hiroki, Watanabe, Yoshinori, Nandakumar, Jayakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755706/
https://www.ncbi.nlm.nih.gov/pubmed/29083414
http://dx.doi.org/10.1038/nsmb.3493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755706/
https://www.ncbi.nlm.nih.gov/pubmed/29083414
http://dx.doi.org/10.1038/nsmb.3493

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