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Dissecting the telomere-inner nuclear membrane interface formed in meiosis

Tethering telomeres to the inner nuclear membrane (INM) allows for homologous chromosome pairing during meiosis. A meiosis-specific protein TERB1 binds the telomeric protein TRF1 to establish telomere-INM connectivity and is essential for mouse fertility. Here we solve the structure of the human TRF...

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Detalles Bibliográficos
Autores principales:	Pendlebury, Devon F., Fujiwara, Yasuhiro, Tesmer, Valerie M., Smith, Eric M., Shibuya, Hiroki, Watanabe, Yoshinori, Nandakumar, Jayakrishnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755706/ https://www.ncbi.nlm.nih.gov/pubmed/29083414 http://dx.doi.org/10.1038/nsmb.3493

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