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The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ

Several studies have demonstrated that specific 14-3-3 isoforms are frequently elevated in cancer and that these proteins play a role in human tumorigenesis. 14-3-3γ, an isoform recently demonstrated to function as an oncoprotein, is overexpressed in a variety of human cancers; however, its role in...

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Detalles Bibliográficos
Autores principales: Gomes, Cecil J., Centuori, Sara M., Harman, Michael W., Putnam, Charles W., Wolgemuth, Charles W., Martinez, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755723/
https://www.ncbi.nlm.nih.gov/pubmed/29321819
http://dx.doi.org/10.18632/genesandcancer.161