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Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice
The act of selecting aptamers against blood serum leads to deep libraries of oligonucleotide sequences that bind to a range of epitopes in blood. In this study we developed an enriched aptamer library by performing positive selection against a pool of blood serum samples from transgenic mice (P301S)...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755763/ https://www.ncbi.nlm.nih.gov/pubmed/29304088 http://dx.doi.org/10.1371/journal.pone.0190212 |