Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy

Tyrosine kinase 2 (TYK2) is a member of the Janus kinases family implicated in the signal transduction of type I interferons and several interleukins. It has been described that genetic mutations within TYK2 lead to multiple deleterious effects in the immune response. In this work, we have analyzed...

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Detalles Bibliográficos
Autores principales: Leon Rodriguez, Daniel A., Acosta-Herrera, Marialbert, Carmona, F. David, Dolade, Nuria, Vargas, Sofia, Echeverría, Luis Eduardo, González, Clara Isabel, Martin, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755805/
https://www.ncbi.nlm.nih.gov/pubmed/29304122
http://dx.doi.org/10.1371/journal.pone.0190591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755805/
https://www.ncbi.nlm.nih.gov/pubmed/29304122
http://dx.doi.org/10.1371/journal.pone.0190591

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