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Prior exposure to corticosterone markedly enhances and prolongs the neuroinflammatory response to systemic challenge with LPS

Systemic exposure to the inflammagen and bacterial endotoxin lipopolysaccharide (LPS) has been widely used to evaluate inflammation and sickness behavior. While many inflammatory conditions occur in the periphery, it is well established that peripheral inflammation can affect the brain. Neuroinflamm...

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Detalles Bibliográficos
Autores principales: Kelly, Kimberly A., Michalovicz, Lindsay T., Miller, Julie V., Castranova, Vincent, Miller, Diane B., O’Callaghan, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755880/
https://www.ncbi.nlm.nih.gov/pubmed/29304053
http://dx.doi.org/10.1371/journal.pone.0190546