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Prior exposure to corticosterone markedly enhances and prolongs the neuroinflammatory response to systemic challenge with LPS
Systemic exposure to the inflammagen and bacterial endotoxin lipopolysaccharide (LPS) has been widely used to evaluate inflammation and sickness behavior. While many inflammatory conditions occur in the periphery, it is well established that peripheral inflammation can affect the brain. Neuroinflamm...
Autores principales: | Kelly, Kimberly A., Michalovicz, Lindsay T., Miller, Julie V., Castranova, Vincent, Miller, Diane B., O’Callaghan, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755880/ https://www.ncbi.nlm.nih.gov/pubmed/29304053 http://dx.doi.org/10.1371/journal.pone.0190546 |
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