Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

Hyperphosphatemia and vascular calcification are frequent complications of chronic renal failure and bone morphogenetic protein 7 (BMP7) has been shown to protect against development of vascular calcification in uremia. The present investigation examined the potential reversibility of established ur...

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Detalles Bibliográficos
Autores principales: Gravesen, Eva, Lerche Mace, Maria, Nordholm, Anders, Hofman-Bang, Jacob, Hruska, Keith, Haagen Nielsen, Carsten, Kjær, Andreas, Olgaard, Klaus, Lewin, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755916/
https://www.ncbi.nlm.nih.gov/pubmed/29304096
http://dx.doi.org/10.1371/journal.pone.0190820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755916/
https://www.ncbi.nlm.nih.gov/pubmed/29304096
http://dx.doi.org/10.1371/journal.pone.0190820

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