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Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification
Hyperphosphatemia and vascular calcification are frequent complications of chronic renal failure and bone morphogenetic protein 7 (BMP7) has been shown to protect against development of vascular calcification in uremia. The present investigation examined the potential reversibility of established ur...
Autores principales: | Gravesen, Eva, Lerche Mace, Maria, Nordholm, Anders, Hofman-Bang, Jacob, Hruska, Keith, Haagen Nielsen, Carsten, Kjær, Andreas, Olgaard, Klaus, Lewin, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755916/ https://www.ncbi.nlm.nih.gov/pubmed/29304096 http://dx.doi.org/10.1371/journal.pone.0190820 |
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