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Theoretical perspectives on central chemosensitivity: CO(2)/H(+)-sensitive neurons in the locus coeruleus

Central chemoreceptors are highly sensitive neurons that respond to changes in pH and CO(2) levels. An increase in CO(2)/H(+) typically reflects a rise in the firing rate of these neurons, which stimulates an increase in ventilation. Here, we present an ionic current model that reproduces the basic...

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Detalles Bibliográficos
Autores principales: Quintero, Maria C., Putnam, Robert W., Cordovez, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755939/
https://www.ncbi.nlm.nih.gov/pubmed/29267284
http://dx.doi.org/10.1371/journal.pcbi.1005853