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Orchestration of H3K27 methylation: mechanisms and therapeutic implication

Histone proteins constitute the core component of the nucleosome, the basic unit of chromatin. Chemical modifications of histone proteins affect their interaction with genomic DNA, the accessibility of recognized proteins, and the recruitment of enzymatic complexes to activate or diminish specific t...

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Detalles Bibliográficos
Autores principales: Pan, Mei-Ren, Hsu, Ming-Chuan, Chen, Li-Tzong, Hung, Wen-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756243/
https://www.ncbi.nlm.nih.gov/pubmed/28717873
http://dx.doi.org/10.1007/s00018-017-2596-8