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Suppression of the toll-like receptor 7-dependent type I interferon production pathway by autophagy resulting from enterovirus 71 and coxsackievirus A16 infections facilitates their replication

Toll-like receptors (TLRs) act as molecular sentinels, detecting invading viral pathogens and triggering host innate immune responses, including autophagy. However, many viruses have evolved a series of strategies to manipulate autophagy for their own benefit. Enterovirus 71 (EV71) and coxsackieviru...

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Detalles Bibliográficos
Autores principales: Song, Jie, Hu, Yajie, Li, Jiaqi, Zheng, Huiwen, Wang, Jingjing, Guo, Lei, Shi, Haijng, Liu, Longding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756282/
https://www.ncbi.nlm.nih.gov/pubmed/29052054
http://dx.doi.org/10.1007/s00705-017-3592-x