Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy. The aim of our study was t...

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Detalles Bibliográficos
Autores principales: O’Connor, David, Enshaei, Amir, Bartram, Jack, Hancock, Jeremy, Harrison, Christine J., Hough, Rachael, Samarasinghe, Sujith, Schwab, Claire, Vora, Ajay, Wade, Rachel, Moppett, John, Moorman, Anthony V., Goulden, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2018
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756322/
https://www.ncbi.nlm.nih.gov/pubmed/29131699
http://dx.doi.org/10.1200/JCO.2017.74.0449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756322/
https://www.ncbi.nlm.nih.gov/pubmed/29131699
http://dx.doi.org/10.1200/JCO.2017.74.0449

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