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Regulation of pancreatic stellate cell activation by Notch3

BACKGROUND: Activated pancreatic stellate cells (PaSCs) are the key cellular source of cancer-associated fibroblasts in the pancreatic stroma of patients with pancreatic ductal adenocarcinoma (PDAC), however, the activation mechanism of PaSCs is not yet known. The Notch signaling pathway, components...

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Detalles Bibliográficos
Autores principales: Song, Haiyan, Zhang, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756326/
https://www.ncbi.nlm.nih.gov/pubmed/29304760
http://dx.doi.org/10.1186/s12885-017-3957-2