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Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers

BACKGROUND: Elevation of the transcription factor HIF-1 is a prominent mediator of not only processes that accompany hypoxia, but also the tumor microenvironment and tissue regeneration. This study uses mediators of “chemical hypoxia” to ask the question whether HIF-1α elevation in a healthy epithel...

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Detalles Bibliográficos
Autores principales: DiGuilio, K. M., Valenzano, M. C., Rybakovsky, E., Mullin, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756372/
https://www.ncbi.nlm.nih.gov/pubmed/29304733
http://dx.doi.org/10.1186/s12876-017-0731-5