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Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction

BACKGROUND: Airway smooth muscle contraction is critical for maintenance of appropriate airway tone, and has been implicated in asthma pathogenesis. Smooth muscle contraction requires an “engine” (myosin activation) and a “transmission system” (actin cytoskeletal remodeling). However, the mechanisms...

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Detalles Bibliográficos
Autores principales: Wang, Yinna, Rezey, Alyssa C., Wang, Ruping, Tang, Dale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756382/
https://www.ncbi.nlm.nih.gov/pubmed/29304860
http://dx.doi.org/10.1186/s12931-017-0709-4