Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC

BACKGROUND: Patients with Echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) positive lung cancer are sensitive to ALK-kinase inhibitors. TAE684 is a potent second generation ALK inhibitor that overcomes Crizotinib resistance. Radiotherapy is an integral therape...

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Detalles Bibliográficos
Autores principales: Dai, Ying, Wei, Quanxiang, Schwager, Christian, Hanne, Janina, Zhou, Cheng, Herfarth, Klaus, Rieken, Stefan, Lipson, Kenneth E., Debus, Jürgen, Abdollahi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756447/
https://www.ncbi.nlm.nih.gov/pubmed/29304828
http://dx.doi.org/10.1186/s13014-017-0947-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756447/
https://www.ncbi.nlm.nih.gov/pubmed/29304828
http://dx.doi.org/10.1186/s13014-017-0947-0

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