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Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC
BACKGROUND: Patients with Echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) positive lung cancer are sensitive to ALK-kinase inhibitors. TAE684 is a potent second generation ALK inhibitor that overcomes Crizotinib resistance. Radiotherapy is an integral therape...
Autores principales: | Dai, Ying, Wei, Quanxiang, Schwager, Christian, Hanne, Janina, Zhou, Cheng, Herfarth, Klaus, Rieken, Stefan, Lipson, Kenneth E., Debus, Jürgen, Abdollahi, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756447/ https://www.ncbi.nlm.nih.gov/pubmed/29304828 http://dx.doi.org/10.1186/s13014-017-0947-0 |
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