Evaluation of a novel line probe assay to detect resistance to pyrazinamide, a key drug used for tuberculosis treatment()

OBJECTIVES: The development of rapid molecular diagnostic assays for pyrazinamide (PZA) resistance is considered technically challenging as mutations are highly diverse, scattered along the full length of the pncA gene and not all are associated with PZA resistance. We evaluated the performance of t...

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Detalles Bibliográficos
Autores principales: Driesen, M., Kondo, Y., de Jong, B.C., Torrea, G., Asnong, S., Desmaretz, C., Mostofa, K.S.M., Tahseen, S., Whitfield, M.G., Cirillo, D.M., Miotto, P., Cabibbe, A.M., Rigouts, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756542/
https://www.ncbi.nlm.nih.gov/pubmed/28587904
http://dx.doi.org/10.1016/j.cmi.2017.05.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756542/
https://www.ncbi.nlm.nih.gov/pubmed/28587904
http://dx.doi.org/10.1016/j.cmi.2017.05.026

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