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Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization

Structural variations of the well-known guanine quartet (G(4)) motif in nucleic acid structures, namely substitution of two guanine bases (G) by two adenine (A) nucleobases in mutual trans positions, are discussed and studied by density functional theory (DFT) methods. This work was initiated by thr...

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Detalles Bibliográficos
Autores principales: Megger, Dominik A., Lax, Patrick M., Paauwe, Jeroen, Fonseca Guerra, Célia, Lippert, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756560/
https://www.ncbi.nlm.nih.gov/pubmed/29218641
http://dx.doi.org/10.1007/s00775-017-1507-7