In Vitro Biotransformation, Safety, and Chemopreventive Action of Novel 8-Methoxy-Purine-2,6-Dione Derivatives

Metabolic stability, mutagenicity, antimutagenicity, and the ability to scavenge free radicals of four novel 8-methoxy-purine-2,6-dione derivatives (compounds 1–4) demonstrating analgesic and anti-inflammatory properties were determined. Metabolic stability was evaluated in Cunninghamella and micros...

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Detalles Bibliográficos
Autores principales: Marć, Małgorzata Anna, Domínguez-Álvarez, Enrique, Słoczyńska, Karolina, Żmudzki, Paweł, Chłoń-Rzepa, Grażyna, Pękala, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756575/
https://www.ncbi.nlm.nih.gov/pubmed/28624999
http://dx.doi.org/10.1007/s12010-017-2527-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756575/
https://www.ncbi.nlm.nih.gov/pubmed/28624999
http://dx.doi.org/10.1007/s12010-017-2527-z

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