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Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex

BACKGROUND: Exposure of the developing brain to immune mediators, including antibodies, is postulated to increase risk for neurodevelopmental disorders and neurodegenerative disease. It has been suggested that immunoglobulin G-immune complexes (IgG-IC) activate Fc gamma receptors (FcγR) expressed on...

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Detalles Bibliográficos
Autores principales: Stamou, Marianna, Grodzki, Ana Cristina, van Oostrum, Marc, Wollscheid, Bernd, Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756609/
https://www.ncbi.nlm.nih.gov/pubmed/29306331
http://dx.doi.org/10.1186/s12974-017-1050-z