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Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer

E3 ubiquitin (UB) ligases E4B and carboxyl terminus of Hsc70-interacting protein (CHIP) use a common U-box motif to transfer UB from E1 and E2 enzymes to their substrate proteins and regulate diverse cellular processes. To profile their ubiquitination targets in the cell, we used phage display to en...

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Detalles Bibliográficos
Autores principales: Bhuripanyo, Karan, Wang, Yiyang, Liu, Xianpeng, Zhou, Li, Liu, Ruochuan, Duong, Duc, Zhao, Bo, Bi, Yingtao, Zhou, Han, Chen, Geng, Seyfried, Nicholas T., Chazin, Walter J., Kiyokawa, Hiroaki, Yin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756662/
https://www.ncbi.nlm.nih.gov/pubmed/29326975
http://dx.doi.org/10.1126/sciadv.1701393