Udenafil, a Phosphodiesterase 5 Inhibitor, Reduces Body Weight in High-Fat-Fed Mice

PURPOSE: High-fat (HF) feeding induces hypothalamic leptin resistance via the activation of toll-like receptor 4 (TLR4). TLR4 deficiency confers resistance to diet-induced obesity. Udenafil, an anti-impotence drug, inhibits TLR4 in airway epithelial cells in vitro. In this study, we evaluated whethe...

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Detalles Bibliográficos
Autores principales: Ryu, Seong Yul, Choi, Yoon-Jung, Park, So-Young, Kim, Jong-Yeon, Kim, Yong-Dae, Kim, Yong-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756806/
https://www.ncbi.nlm.nih.gov/pubmed/29164831
http://dx.doi.org/10.5534/wjmh.17028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756806/
https://www.ncbi.nlm.nih.gov/pubmed/29164831
http://dx.doi.org/10.5534/wjmh.17028

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