RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene

Acute kidney injury (AKI) induced by ischemia-reperfusion is a critical conundrum in many clinical settings. Here, this study aimed to determine whether and how RTA-408, a novel oleanane triterpenoid, could confer protection against renal ischemia-reperfusion injury (IRI) in male mice. Mice treated...

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Detalles Bibliográficos
Autores principales: Han, Peng, Qin, Zhiqiang, Tang, Jingyuan, Xu, Zhen, Li, Ran, Jiang, Xuping, Yang, Chengdi, Xing, Qianwei, Qi, Xiaokang, Tang, Min, Zhang, Jiexiu, Shen, Baixin, Wang, Wei, Qin, Chao, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757134/
https://www.ncbi.nlm.nih.gov/pubmed/29435098
http://dx.doi.org/10.1155/2017/7612182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757134/
https://www.ncbi.nlm.nih.gov/pubmed/29435098
http://dx.doi.org/10.1155/2017/7612182

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