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RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene

Acute kidney injury (AKI) induced by ischemia-reperfusion is a critical conundrum in many clinical settings. Here, this study aimed to determine whether and how RTA-408, a novel oleanane triterpenoid, could confer protection against renal ischemia-reperfusion injury (IRI) in male mice. Mice treated...

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Detalles Bibliográficos
Autores principales:	Han, Peng, Qin, Zhiqiang, Tang, Jingyuan, Xu, Zhen, Li, Ran, Jiang, Xuping, Yang, Chengdi, Xing, Qianwei, Qi, Xiaokang, Tang, Min, Zhang, Jiexiu, Shen, Baixin, Wang, Wei, Qin, Chao, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757134/ https://www.ncbi.nlm.nih.gov/pubmed/29435098 http://dx.doi.org/10.1155/2017/7612182

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