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Matrix metalloproteinase‐1 facilitates MSC migration via cleavage of IGF‐2/IGFBP2 complex

The specific mechanism underlying the tumor tropism of human mesenchymal stem cells (MSCs) for cancer is not well defined. We previously showed that the migration potential of MSCs correlated with the expression and protease activity of matrix metalloproteinase (MMP)‐1. Furthermore, highly tumor‐tro...

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Detalles Bibliográficos
Autores principales: Guan, Shou P., Lam, Alan T.L., Newman, Jennifer P., Chua, Kevin L.M., Kok, Catherine Y.L., Chong, Siao T., Chua, Melvin L.K., Lam, Paula Y.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757182/
https://www.ncbi.nlm.nih.gov/pubmed/29321953
http://dx.doi.org/10.1002/2211-5463.12330