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Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance

BACKGROUND: Ovarian cancer has the highest mortality rate among all the gynecological cancers. This is mostly due to the resistance of ovarian cancer to current chemotherapy regimens. Therefore, it is of crucial importance to identify the molecular mechanisms associated with chemoresistance. METHODS...

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Detalles Bibliográficos
Autores principales: Vert, Anna, Castro, Jessica, Ribó, Marc, Vilanova, Maria, Benito, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757493/
https://www.ncbi.nlm.nih.gov/pubmed/29379303
http://dx.doi.org/10.2147/OTT.S154378