Cargando…
Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance
BACKGROUND: Ovarian cancer has the highest mortality rate among all the gynecological cancers. This is mostly due to the resistance of ovarian cancer to current chemotherapy regimens. Therefore, it is of crucial importance to identify the molecular mechanisms associated with chemoresistance. METHODS...
Autores principales: | Vert, Anna, Castro, Jessica, Ribó, Marc, Vilanova, Maria, Benito, Antoni |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757493/ https://www.ncbi.nlm.nih.gov/pubmed/29379303 http://dx.doi.org/10.2147/OTT.S154378 |
Ejemplares similares
-
Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase
por: Vert, Anna, et al.
Publicado: (2016) -
A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells
por: Vert, Anna, et al.
Publicado: (2016) -
Carnosine Potentiates Doxorubicin-Induced Cytotoxicity in Resistant NCI/ADR-RES Cells by Inhibiting P-Glycoprotein—In Silico and In Vitro Evidence
por: Morsy, Mohamed A., et al.
Publicado: (2022) -
In silico and in vitro identification of secoisolariciresinol as a re-sensitizer of P-glycoprotein-dependent doxorubicin-resistance NCI/ADR-RES cancer cells
por: Morsy, Mohamed A., et al.
Publicado: (2020) -
Strengths and Challenges of Secretory Ribonucleases as AntiTumor Agents
por: Castro, Jessica, et al.
Publicado: (2021)