miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells

INTRODUCTION: miR-99a-5p, known to play an important role in mammalian target of rapamycin (mTOR) regulation, is downregulated in human bladder cancer. The study aimed to investigate the anticancer activity of miR-99a-5p and the possible mechanism associated with mTOR in bladder cancer cells. MATERI...

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Detalles Bibliográficos
Autores principales: Tsai, Te-Fu, Lin, Ji-Fan, Chou, Kuang-Yu, Lin, Yi-Chia, Chen, Hung-En, Hwang, Thomas I-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757495/
https://www.ncbi.nlm.nih.gov/pubmed/29379304
http://dx.doi.org/10.2147/OTT.S114276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757495/
https://www.ncbi.nlm.nih.gov/pubmed/29379304
http://dx.doi.org/10.2147/OTT.S114276

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