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RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression

INTRODUCTION: Accumulating evidence indicates that RACK1 is involved in the progression of tumors. We aimed to evaluate the function of RACK1 in esophageal squamous cell carcinoma (ESCC) and its role in the mechanism of chemotherapy resistance. MATERIALS AND METHODS: Transfected ESCC cell lines with...

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Detalles Bibliográficos
Autores principales: Liu, Bowen, Wang, Cong, Chen, Pengxiang, Cheng, Bo, Cheng, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757499/
https://www.ncbi.nlm.nih.gov/pubmed/29379302
http://dx.doi.org/10.2147/OTT.S152818