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Towards an Understanding of Energy Impairment in Huntington’s Disease Brain
This review systematically examines the evidence for shifts in flux through energy generating biochemical pathways in Huntington’s disease (HD) brains from humans and model systems. Compromise of the electron transport chain (ETC) appears not to be the primary or earliest metabolic change in HD path...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757653/ https://www.ncbi.nlm.nih.gov/pubmed/29125492 http://dx.doi.org/10.3233/JHD-170264 |