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Towards an Understanding of Energy Impairment in Huntington’s Disease Brain

This review systematically examines the evidence for shifts in flux through energy generating biochemical pathways in Huntington’s disease (HD) brains from humans and model systems. Compromise of the electron transport chain (ETC) appears not to be the primary or earliest metabolic change in HD path...

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Detalles Bibliográficos
Autor principal: Dubinsky, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757653/
https://www.ncbi.nlm.nih.gov/pubmed/29125492
http://dx.doi.org/10.3233/JHD-170264