Cargando…

Towards an Understanding of Energy Impairment in Huntington’s Disease Brain

This review systematically examines the evidence for shifts in flux through energy generating biochemical pathways in Huntington’s disease (HD) brains from humans and model systems. Compromise of the electron transport chain (ETC) appears not to be the primary or earliest metabolic change in HD path...

Descripción completa

Detalles Bibliográficos
Autor principal:	Dubinsky, Janet M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757653/ https://www.ncbi.nlm.nih.gov/pubmed/29125492 http://dx.doi.org/10.3233/JHD-170264

Ejemplares similares

Huntington disease: Advances in the understanding of its mechanisms()
por: Gatto, Emilia M., et al.
Publicado: (2020)

Understanding histone deacetylation in Huntington’s disease
por: Valor, Luis Miguel
Publicado: (2016)

Impaired Cerebrovascular Reactivity in Huntington’s Disease
por: Chan, Suk Tak, et al.
Publicado: (2021)

Do Changes in Synaptic Autophagy Underlie the Cognitive Impairments in Huntington’s Disease?
por: Grosso Jasutkar, Hilary, et al.
Publicado: (2021)

The regulatory roles of microRNAs toward pathogenesis and treatments in Huntington's disease
por: Tung, Chih-Wei, et al.
Publicado: (2021)

The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias
por: Davies, Janet E, et al.
Publicado: (2007)

Automated Assessment of Movement Impairment in Huntington’s Disease
Publicado: (2018)

Huntington’s Disease: Understanding Its Novel Drugs and Treatments
por: Dhingra, Hitaansh, et al.
Publicado: (2023)

Irritability in Huntington’s Disease
por: Karagas, Nicholas E., et al.
Publicado: (2020)

Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain
por: Fukuoka, Masashi, et al.
Publicado: (2018)

Cognitive Dysfunction Contributes to Mobility Impairments in Huntington’s Disease
por: Kloos, Anne D., et al.
Publicado: (2017)

Brain Microbiota in Huntington’s Disease Patients
por: Alonso, Ruth, et al.
Publicado: (2019)

The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?
por: Schipper-Krom, Sabine, et al.
Publicado: (2012)

No evidence of impaired gastric emptying in early Huntington‘s Disease
por: Saft, Carsten, et al.
Publicado: (2011)

Pridopidine activates neuroprotective pathways impaired in Huntington Disease
por: Geva, Michal, et al.
Publicado: (2016)

Impaired Redox Signaling in Huntington’s Disease: Therapeutic Implications
por: Paul, Bindu D., et al.
Publicado: (2019)

Mild Cognitive Impairment as an Early Landmark in Huntington's Disease
por: Zhang, Ying, et al.
Publicado: (2021)

Measuring the functional impact of cognitive impairment in Huntington’s disease
por: Horta-Barba, Andrea, et al.
Publicado: (2022)

Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington’s disease provides in vivo evidence for impaired energy metabolism
por: van den Bogaard, Simon J. A., et al.
Publicado: (2011)

Huntington Disease in Asia
por: Xu, Miao, et al.
Publicado: (2015)

Neuropsychiatric Burden in Huntington’s Disease
por: Paoli, Ricardo Augusto, et al.
Publicado: (2017)

Therapeutic Strategies in Huntington's Disease
por: Kanazawa, Ichiro
Publicado: (2006)

Neurodegenerative processes in Huntington's disease
por: Bano, D, et al.
Publicado: (2011)

PET Imaging in Huntington’s Disease
por: Roussakis, Andreas-Antonios, et al.
Publicado: (2015)

The Neurodevelopmental Hypothesis of Huntington’s Disease
por: van der Plas, Ellen, et al.
Publicado: (2020)

Therapeutic Advances for Huntington’s Disease
por: Kumar, Ashok, et al.
Publicado: (2020)

DNA Methylation in Huntington’s Disease
por: Zsindely, Nóra, et al.
Publicado: (2021)

Olfactory Dysfunction in Huntington’s Disease
por: Patino, Jorge, et al.
Publicado: (2021)

Dual tasking impairments are associated with striatal pathology in Huntington’s disease
por: Lo, Johnny, et al.
Publicado: (2020)

Deep Brain Stimulation in Huntington’s Disease—Preliminary Evidence on Pathophysiology, Efficacy and Safety
por: Wojtecki, Lars, et al.
Publicado: (2016)

What the Gut Tells the Brain—Is There a Link between Microbiota and Huntington’s Disease?
por: Wronka, Dorota, et al.
Publicado: (2023)

Brain structure in juvenile-onset Huntington disease
por: Tereshchenko, Alexander, et al.
Publicado: (2019)

Structural brain correlates of dementia in Huntington’s disease
por: Martinez-Horta, Saul, et al.
Publicado: (2020)

Unraveling Molecular and Genetic Insights into Neurodegenerative Diseases: Advances in Understanding Alzheimer’s, Parkinson’s, and Huntington’s Diseases and Amyotrophic Lateral Sclerosis
por: Ciurea, Alexandru Vlad, et al.
Publicado: (2023)

Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease
por: Di Pardo, Alba, et al.
Publicado: (2017)

SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington’s Disease Mice
por: Tulino, Raffaella, et al.
Publicado: (2016)

Emotion recognition and experience in Huntington's disease: Is there a differential impairment?
por: Ille, Rottraut, et al.
Publicado: (2011)

Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington’s disease
por: Hwang, Sunhee, et al.
Publicado: (2015)

Arginine methylation of RNA-binding proteins is impaired in Huntington’s disease
por: Ratovitski, Tamara, et al.
Publicado: (2023)

Exploring the brain-body composition relationship in Huntington’s disease
por: Turner, Mitchell, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jt513m8m25urqo9mvvahug8lju