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Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansions in the IT15 gene which encodes the huntingtin (HTT) protein. Currently, no treatments capable of preventing or slowing disease progression exist. Disease modifying therapeutics for HD would...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757655/ https://www.ncbi.nlm.nih.gov/pubmed/29254102 http://dx.doi.org/10.3233/JHD-170275 |