Cargando…

Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington’s Disease

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansions in the IT15 gene which encodes the huntingtin (HTT) protein. Currently, no treatments capable of preventing or slowing disease progression exist. Disease modifying therapeutics for HD would...

Descripción completa

Detalles Bibliográficos
Autor principal: Simmons, Danielle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757655/
https://www.ncbi.nlm.nih.gov/pubmed/29254102
http://dx.doi.org/10.3233/JHD-170275