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Cyclin D/CDK4/6 activity controls G1 length in mammalian cells
The length of the G1 phase in the cell cycle shows significant variability in different cell types and tissue types. To gain insights into the control of G1 length, we generated an E2F activity reporter that captures free E2F activity after dissociation from Rb sequestration and followed its kinetic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757913/ https://www.ncbi.nlm.nih.gov/pubmed/29309421 http://dx.doi.org/10.1371/journal.pone.0185637 |