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Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

Detection of viral nucleic acids plays a critical role in the induction of intracellular host immune defences. However, the temporal recruitment of immune regulators to infecting viral genomes remains poorly defined due to the technical difficulties associated with low genome copy-number detection....

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Detalles Bibliográficos
Autores principales: Alandijany, Thamir, Roberts, Ashley P. E., Conn, Kristen L., Loney, Colin, McFarlane, Steven, Orr, Anne, Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757968/
https://www.ncbi.nlm.nih.gov/pubmed/29309427
http://dx.doi.org/10.1371/journal.ppat.1006769