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The methylenetetrahydrofolate reductase 677T-1298C haplotype is a risk factor for acute lymphoblastic leukemia in children

The etiology of acute lymphoblastic leukemia (ALL) is complex, linked with both environmental exposures and genetic factors. Functional variants of the methylenetetrahydrofolate reductase (MTHFR) gene result in disturbance in folate metabolism and may affect susceptibility to cancer. The study was p...

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Detalles Bibliográficos
Autores principales: Kałużna, Ewelina Maria, Strauss, Ewa, Świątek-Kościelna, Bogna, Zając-Spychała, Olga, Gowin, Ewelina, Nowak, Jerzy S., Rembowska, Jolanta, Januszkiewicz-Lewandowska, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758194/
https://www.ncbi.nlm.nih.gov/pubmed/29390492
http://dx.doi.org/10.1097/MD.0000000000009290