Cargando…

Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome

The neurodevelopmental disorder Angelman syndrome (AS) is characterized by intellectual disability, motor dysfunction, distinct behavioral aspects, and epilepsy. AS is caused by a loss of the maternally expressed UBE3A gene, and many of the symptoms are recapitulated in a Ube3a mouse model of this s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tiantian, van Woerden, Geeske M., Elgersma, Ype, Borst, J. Gerard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758499/
https://www.ncbi.nlm.nih.gov/pubmed/29354033
http://dx.doi.org/10.3389/fncel.2017.00418