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Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome
The neurodevelopmental disorder Angelman syndrome (AS) is characterized by intellectual disability, motor dysfunction, distinct behavioral aspects, and epilepsy. AS is caused by a loss of the maternally expressed UBE3A gene, and many of the symptoms are recapitulated in a Ube3a mouse model of this s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758499/ https://www.ncbi.nlm.nih.gov/pubmed/29354033 http://dx.doi.org/10.3389/fncel.2017.00418 |