Inhibition of RGMa alleviates symptoms in a rat model of neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG), an antibody that selectively binds to the aquaporin-4. Here, we established a localized NMO model by injecting NMO-IgG into the spinal cord, and assessed the efficacy of treating its NMO-like symptoms...

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Detalles Bibliográficos
Autores principales: Harada, Kana, Fujita, Yuki, Okuno, Tatsusada, Tanabe, Shogo, Koyama, Yoshihisa, Mochizuki, Hideki, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758562/
https://www.ncbi.nlm.nih.gov/pubmed/29311561
http://dx.doi.org/10.1038/s41598-017-18362-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758562/
https://www.ncbi.nlm.nih.gov/pubmed/29311561
http://dx.doi.org/10.1038/s41598-017-18362-2

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