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TRAF2 in osteotropic breast cancer cells enhances skeletal tumour growth and promotes osteolysis

NFκB plays an important role in inflammation and bone remodelling. Tumour necrosis factor receptor associated factor 2 (TRAF2), a key component of NFκB signalling, has been identified as an oncogene, but its role in the regulation of breast cancer osteolytic metastasis remains unknown. Here, we repo...

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Detalles Bibliográficos
Autores principales: Peramuhendige, Prabha, Marino, Silvia, Bishop, Ryan T., de Ridder, Daniëlle, Khogeer, Asim, Baldini, Isabella, Capulli, Mattia, Rucci, Nadia, Idris, Aymen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758572/
https://www.ncbi.nlm.nih.gov/pubmed/29311633
http://dx.doi.org/10.1038/s41598-017-18327-5