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Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle

The development of metabolic approaches towards understanding the origins of life, which have focused mainly on the citric acid (TCA) cycle, have languished—primarily due to a lack of experimentally demonstrable and sustainable cycle(s) of reactions. We show here the existence of a protometabolic an...

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Detalles Bibliográficos
Autores principales: Springsteen, Greg, Yerabolu, Jayasudhan Reddy, Nelson, Julia, Rhea, Chandler Joel, Krishnamurthy, Ramanarayanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758577/
https://www.ncbi.nlm.nih.gov/pubmed/29311556
http://dx.doi.org/10.1038/s41467-017-02591-0