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Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle
The development of metabolic approaches towards understanding the origins of life, which have focused mainly on the citric acid (TCA) cycle, have languished—primarily due to a lack of experimentally demonstrable and sustainable cycle(s) of reactions. We show here the existence of a protometabolic an...
Autores principales: | Springsteen, Greg, Yerabolu, Jayasudhan Reddy, Nelson, Julia, Rhea, Chandler Joel, Krishnamurthy, Ramanarayanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758577/ https://www.ncbi.nlm.nih.gov/pubmed/29311556 http://dx.doi.org/10.1038/s41467-017-02591-0 |
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