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Generation of Functional Dopaminergic Neurons from Reprogramming Fibroblasts by Nonviral-based Mesoporous Silica Nanoparticles

Direct-lineage conversion of the somatic cell by reprogramming, in which mature cells were fully converted into a variety of other cell types bypassing an intermediate pluripotent state, is a promising regenerative medicine approach. Due to the risk of tumorigenesis by viral methods, a non-viral car...

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Detalles Bibliográficos
Autores principales: Chang, Jen-Hsuan, Tsai, Ping-Hsing, Wang, Kai-Yi, Wei, Yu-Ting, Chiou, Shih-Hwa, Mou, Chung-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758610/
https://www.ncbi.nlm.nih.gov/pubmed/29311646
http://dx.doi.org/10.1038/s41598-017-18324-8