Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPARγ

Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the nuclear receptor superfamily. It functions as a ligand-activated transcription factor and plays important roles in the regulation of adipocyte differentiation, insulin resistance, and inflammation. Here, we report the crystal st...

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Detalles Bibliográficos
Autores principales: Jang, Jun Young, Bae, Hwan, Lee, Yong Jae, Choi, Young Il, Kim, Hyun-Jung, Park, Seung Bum, Suh, Se Won, Kim, Sang Wan, Han, Byung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758645/
https://www.ncbi.nlm.nih.gov/pubmed/29311579
http://dx.doi.org/10.1038/s41598-017-18274-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758645/
https://www.ncbi.nlm.nih.gov/pubmed/29311579
http://dx.doi.org/10.1038/s41598-017-18274-1

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