Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy

Insulin resistance is a critical process in the initiation and progression of diabetic nephropathy (DN). Alprostadil (Prostaglandin E1, PGE1) had protective effects on renal function. However, it is unknown whether PGE1 inhibited insulin resistance in renal tubule epithelial cells via autophagy, whi...

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Detalles Bibliográficos
Autores principales: Wei, Wei, An, Xing-Rong, Jin, Shi-Jie, Li, Xiao-Xue, Xu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758726/
https://www.ncbi.nlm.nih.gov/pubmed/29311680
http://dx.doi.org/10.1038/s41598-017-18427-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758726/
https://www.ncbi.nlm.nih.gov/pubmed/29311680
http://dx.doi.org/10.1038/s41598-017-18427-2

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